ActiBiso™-GDL(Gluconolactone)--Gentle skin rejuvenation revolution · Opening up a new era of "smart skin rejuvenation" that can be used with confidence in sensitive skin

Consumers have long faced the contradiction of "high efficiency" and "gentleness" in the field of skin care.  ActiBiso™-GDL( Gluconolactone) ,developed by Suzhou Sunland Pharmaceutical Technology Co., Ltd., with its unique molecular structure and multiple functions, is gradually replacing traditional acids and becoming a star raw material for sensitive muscles.

1. Traceability of ingredients: The gentle power of natural gifts

ActiBiso™-GDL(Gluconolactone) is a kind of naturally occurring polyhydroxy acid, which is obtained from glucose by biological fermentation. It is a fine white crystalline powder, easily soluble in water and slightly sweet in taste.

Through the research of Sunland R&D team, we fully explored its multiple characteristics:

• Gentle and low stimulation: The molecule is not easy to penetrate the stratum corneum, and its irritability is much lower than that of glycolic acid and salicylic acid
• Strong chelation: Complex metal ions to reduce oxidative stress and protect skin barriers
• Superior pH adaptability: Stable in the pH range of 3.5–4.5, and highly compatible with the natural acidic environment of skin.
• Excellent moisturizing properties: Enhance the hydration of the stratum corneum, enhance skin feeling and barrier health

2. Core effects: All-round smart skin rejuvenation ingredients

(1) Gentle skin rejuvenation · Sensitive muscle peace of mind.

• Promote gentle metabolism of old waste keratin and improve rough pores
• Strengthen the cohesion of stratum corneum and avoid excessive injury.
• According to clinical data, the improvement effect of 14% GDL on pores and texture is ≈ 8% glycolic acid, but the irritation is reduced by 67%.

(2) Antioxidant repair ·Self-contained "anti-oxidation super power"

• Chelate metal ions such as iron and copper to block the generation of free radicals.
• The ROS was significantly removed, and the level of free radicals was significantly reduced.
• Experiments show that the antioxidant capacity of 5% GDL is ≈ 2% vitamin C.

(3) Moisturizing and soothing · Brushing with acid will not cause skin damage or blackness.

• Down-regulating inflammatory factors IL-6 and TNF-α to relieve redness and tingling.
• Clinical confirmation: significantly lower irritation in the range of 4%–15% than AHA/BHA, and even suitable for rosacea skin

(4) Brighten skin tone · Improve photoaging

• Improve the moisture content of the stratum corneum, making the skin smoother and more delicate
• Gently accelerate metabolism, assist in fading acne scars and pigmentation, and rejuvenating natural and translucent

3. Market Breakthrough: The Differentiated Value of ActiBiso™-GDL

As a star ingredient that Sunland focuses on creating, ActiBiso™-GDL directly hits the pain points of the industry:

• Cracking the problem of "gentle ≠ efficient"
•  40% of consumers give up acid products due to sting and peeling
•  35% Sensitive skin desires to brush soreness but dare not try
•  GDL provides new solutions with “low stimulation, high efficacy”
• The skin care market is growing rapidly in accordance with the effects of sensitive skin
• Chinese sensitive skin population accounts for as high as 54%
• The annual growth rate of "gentle acid" category is >25%, while the traditional acid is less than 10%
• Adapt to multiple dosage forms and ingredients
• Suitable for use in toners, essences, masks, and emulsions.
• Highly compatible with common soothing and repair ingredients such as nicotinamide, panthenol, and Centella asiatica

4. Application direction: Unlimited innovative product potential

• Sensitive skin rejuvenation series
•  Daily essence: 5–8% GDL + Red Mycohol + Ceramide
•  Cycle mask: 14% GDL + Panthenol + Centella Snow Grass
• Compound acid synergy
•  GDL + Lactonic Acid: Gently brighten, strengthens moisturizing
•  GDL + salicylic acid: pore purification, reducing irritation
•  GDL + azelaic acid: improves oily acne skin and relieves inflammation
• Antioxidant and anti-aging formula
•  GDL + Ergothionine/Aidobenzene: Resistant to photoaging and delicate skin
•  GDL + polypeptide: promotes collagen production and rejuvenates the skin
• Men's skin care and oily acne skin conditioning
•  Repair after shaving to relieve dullness and roughness
•  Combined with oil control ingredients to improve oil secretion and acne problems
• Innovative dosage form for membrane liquid separation
•  Keep the active ingredients fresh
•  Give high-end products a unique sense of ritual

5.R&D and innovation guarantee

Suzhou Sunland Pharmaceutical Technology Co., Ltd. has always adhered to the concept of "science-driven beauty" and focused on the research and development and industrialization of pharmaceutical-grade skin care active ingredients.

Relying on core technology platforms such as polyhydroxy acids (PHA), polypeptides, Sunland continues to provide global skin care brands with efficient, safe and differentiated solutions.

ActiBiso™-GDL（Gluconolactone）is one of Sunland's representative works to transform scientific research results into skin care innovation, bringing new and gentle and efficient possibilities to effective skin care.

6.Conclusion

ActiBiso™-GDL（Gluconolactone） is not only a innovative ingredient for gentle skin rejuvenation, but also a new multi-effect skin care option that integrates skin rejuvenation, antioxidant, moisturizing and soothing.

It provides safety solutions for sensitive skin, opens up new paths for effective skin care, and provides unlimited possibilities for brands to create differentiated products.